The long noncoding RNA HORAS5 mediates castration‐resistant prostate cancer survival by activating the androgen receptor transcriptional program

The long noncoding RNA HORAS5 mediates castration‐resistant prostate cancer survival by activating the androgen receptor transcriptional program

Prostate cancer (PCa) is driven by the androgen receptor (AR)‐signaling axis. Hormonal therapy often mitigates PCa progression, but a notable number of cases progress to castration‐resistant PCa (CRPC). CRPC retains AR activity and is incurable. Long noncoding RNA (lncRNA) represent an uncharted reg...

Full description

Saved in:
Bibliographic Details
Main Authors: Abhijit Parolia, Erik Venalainen, Hui Xue, Rebecca Mather, Dong Lin, Rebecca Wu, Perla Pucci, Jason Rogalski, Joseph R. Evans, Felix Feng, Colin C. Collins, Yuzhuo Wang, Francesco Crea
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Molecular Oncology
Subjects:
androgen independence
HORAS
HORAS5
lncRNA
prostate cancer
Online Access:https://doi.org/10.1002/1878-0261.12471
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/1878-0261.12471

Similar Items