Clinical application value of simultaneous plasma and bronchoalveolar lavage fluid metagenomic next generation sequencing in patients with pneumonia-derived sepsis

Clinical application value of simultaneous plasma and bronchoalveolar lavage fluid metagenomic next generation sequencing in patients with pneumonia-derived sepsis

Abstract Background Despite the increasing use of metagenomic next-generation sequencing (mNGS) in sepsis, identifying clinically relevant pathogens remains challenging. This study was aimed to evaluate the clinical utility of simultaneous plasma and bronchoalveolar lavage fluid (BALF) detection usi...

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Main Authors: Jiayan Li, Dongxu Pan, Yuxin Guo, Bo Zhang, Xinglin Lu, Chen Deng, Feifei Xu, Zongnan Lv, Qinhe Chen, Yafeng Zheng, Shuhao Nong, Lihua Su, Rongfa Qin, Fufu Jiang, Wei Gai, Gang Qin
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Infectious Diseases
Subjects:
Metagenomic next-generation sequencing
Pneumonia-derived sepsis
Dual sample mNGS
Clinical value
Online Access:https://doi.org/10.1186/s12879-024-10292-5
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https://doi.org/10.1186/s12879-024-10292-5

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