Endoplasmic reticulum stress related super-enhancers suppress cuproptosis via glycolysis reprogramming in lung adenocarcinoma
Abstract The role of copper in tumor progression is thought to be a double-edged sword. Moderate levels of copper promote tumor progression, while excess copper induces a novel form of programmed cell death known as cuproptosis. However, the relationship between lung adenocarcinoma (LUAD) and cuprop...
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| Main Authors: | Yan Gu, Hongchang Wang, Wentao Xue, Linjia Zhu, Chenghao Fu, Wenhao Zhang, Guang Mu, Yang Xia, Ke Wei, Jun Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-04-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07613-0 |
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