Coordinated synthesis of aromatic amino acid derived pigments in yeast via global transcriptional engineering

Abstract Background Rational metabolic pathway engineering is capable of boosting upstream flux towards downstream synthesis of target products, such as aromatic amino acid derivatives. However, coordinated synthesis of multiple downstream derivatives faces difficulty of combinatorial optimization o...

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Bibliographic Details
Main Authors: Huimin Xue, Mingshan Li, Yuhui Cui, Dongkui Tian, Duo Liu, Hanjie Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-025-02799-6
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