Microvesicle-Shuttled microRNA-130b Activates the Hepatic Inflammation by Inhibiting Glucocorticoid-Receptor-Mediated Immunosuppression in High-Fat Diet-Induced Obese Mice

Microvesicle-Shuttled microRNA-130b Activates the Hepatic Inflammation by Inhibiting Glucocorticoid-Receptor-Mediated Immunosuppression in High-Fat Diet-Induced Obese Mice

Metabolism-disorder-induced liver diseases have become increasingly prevalent worldwide and are clinically linked to obesity and type 2 diabetes. In addition, a large number of previous literature studies have indicated that plasma miR-130b is a promising biomarker for the early diagnosis and treatm...

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Bibliographic Details
Main Authors: Zhengqiang Han, Lijun Wang, Shiyong Xu, Horsen Zhang, Ji Cheng, Shifeng Pan
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Veterinary Sciences
Subjects:
microvesicles
miRNA-130b
hepatic inflammation
GR-mediated immunosuppression
high-fat diet-induced obese mice
Online Access:https://www.mdpi.com/2306-7381/11/11/565
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