Curcumin alleviates atrazine-induced nephrotoxicity by enhancing mitophagy through PINK1/Parkin signaling pathway in mice

Curcumin alleviates atrazine-induced nephrotoxicity by enhancing mitophagy through PINK1/Parkin signaling pathway in mice

Atrazine (ATR), a widely used herbicide, poses significant environmental and health risks due to its high solubility and adsorption in soil. ATR exposure can lead to nephrotoxicity in humans and animals. Curcumin (Cur), an active compound in Curcuma species, is renowned for its antioxidant and anti-...

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Bibliographic Details
Main Authors: Zhenyu Zou, Xinyi Cheng, Jinyan Chen, Chenghong Xing, Caiying Zhang, Xiaoquan Guo, Huabing Cao, Guoliang Hu, Yu Zhuang
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Pesticide residues
Herbal extracts
Oxidative stress
Autophagy
Apoptosis
Kidney injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325004543
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