Exploring the impact of oxidative stress, excitotoxicity, and apoptosis of retinal ganglion cells in streptozotocin-induced rats: A comprehensive investigation

Chronic hyperglycemia activates pathological molecular pathways, causing high inflammatory mediators, oxidative stress, and growth factors. This process contributes to retinal ganglion cell (RGC) apoptosis through the expression of N-methyl-D-aspartate (NMDA) receptors and nitric oxide (NO). This st...

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Bibliographic Details
Main Authors: Maharani, Arief Sjamsulaksan Kartasasmita, Fifin Luthfia Rahmi, Arief Wildan, Hermawan Istiadi, Annisa Dentin Nugroho, Banundari Rachmawati
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-10-01
Series:Journal of Advanced Pharmaceutical Technology & Research
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Online Access:https://journals.lww.com/japtr/fulltext/2024/15040/exploring_the_impact_of_oxidative_stress,.10.aspx
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