A high-throughput approach to evaluating NCp7 RNA binding activity for HIV-1 drug discovery
The HIV-1 epidemic broadly impacts healthcare. There remains a continued need for improved anti-viral therapies resilient to the development of drug resistance. HIV-1 nucleocapsid protein 7 (NCp7) seems a prime drug target due to its unique nucleic acid chaperone activity required for multiple viral...
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| Main Authors: | Joanna K. Winstone, Rikki Uhrich, Thibault Alle, Brian C. Kraemer |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | SLAS Discovery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S247255522500053X |
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