Exosomal miR-93-3p targets EIF4EBP1 to regulate macrophage polarization and accelerate wound healing post-anal fistula surgery

Exosomal miR-93-3p targets EIF4EBP1 to regulate macrophage polarization and accelerate wound healing post-anal fistula surgery

BackgroundDelayed wound healing following anal fistula (AF) surgery remains a clinical challenge. This study endeavors to identify and validate key exosomal miRNAs that regulate postoperative inflammation after AF surgery by integrating multi-omics analyses with functional assays, and to elucidate t...

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Bibliographic Details
Main Authors: Wei Zhang, Wenzhe Feng, Junhong Chen, Ruoxi Cao, Xi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pharmacology
Subjects:
anal fistula
wound healing
miR-93-3p
target gene EIF4EBP1
MP
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1599633/full
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