Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C

Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C

Background Lymphocytic choriomeningitis virus (LCMV) belongs to the Arenavirus family known for inducing strong cytotoxic T-cell responses in both mice and humans. LCMV has been engineered for the development of cancer immunotherapies, currently undergoing evaluation in phase I/II clinical trials. I...

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Main Authors: Pedro Berraondo, Ignacio Melero, Marisol Quintero, Fernando Aranda, Maite Alvarez, Henning Lauterbach, Myriam Fernandez-Sendin, Claudia Augusta Di Trani, Nuria Ardaiz, Celia Gomar, Angela Bella, Jose Gonzalez-Gomariz, Leire Arrizabalaga, Joan Salvador Russo-Cabrera, Timo Schippers, Klaus K Orlinger
Format: Article
Language:English
Published: BMJ Publishing Group 2024-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/4/e008287.full
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https://jitc.bmj.com/content/12/4/e008287.full

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