Effect of acupuncture treatment for patients with knee osteoarthritis on brain fluctuation amplitude and functional connectivity: a randomized three-armed fMRI study

Effect of acupuncture treatment for patients with knee osteoarthritis on brain fluctuation amplitude and functional connectivity: a randomized three-armed fMRI study

Abstract Background In clinical practice, the overall effect of a treatment includes specific and nonspecific components. Although the analgesic mechanism of specific acupuncture effect has been studied extensively, the understanding of neural basis about nonspecific placebo effect is insufficient....

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Main Authors: Xiao-Ya Wei, Ze-Yi Wang, Guang-Xia Shi, Na Zhang, Jin-Ling Li, Meng-Meng Ren, Jun-Lian Liu, Hang Zhou, Chih-Kai Lee, Jian-Feng Tu, Xu Wang, Cun-Zhi Liu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Acupuncture
ALFF
Functional connectivity
Knee osteoarthritis
fMRI
Online Access:https://doi.org/10.1186/s12906-025-04985-w
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https://doi.org/10.1186/s12906-025-04985-w

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