Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy

Catecholaminergic dysfunction drives postural and locomotor deficits in a mouse model of spinal muscular atrophy

Summary: Development and maintenance of posture is essential behavior for overground mammalian locomotion. Dopamine and noradrenaline strongly influence locomotion, and their dysregulation initiates the development of motor impairments linked to neurodegenerative disease. However, the precise cellul...

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Bibliographic Details
Main Authors: John G. Pagiazitis, Nicolas Delestrée, Leonie Sowoidnich, Nandhini Sivakumar, Christian M. Simon, Athanasios Chatzisotiriou, Maria Albani, George Z. Mentis
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014980
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