Management outcome of knee septic arthritis in neonates and infants:A systematic review

Introduction: Septic arthritis (SA) is considered an orthopedic emergency especially when occurring in infants yet the gold standard for its management is yet to be determined with only a scanty amount of research carried out the detailed outcomes information from different types of treatment used....

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Main Authors: Hilmi Muhammad, Rahadyan Magetsari, Alfin Ihza Trimahendra, Paramita Ayu Saraswati
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Orthopaedic Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2773157X24002133
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author Hilmi Muhammad
Rahadyan Magetsari
Alfin Ihza Trimahendra
Paramita Ayu Saraswati
author_facet Hilmi Muhammad
Rahadyan Magetsari
Alfin Ihza Trimahendra
Paramita Ayu Saraswati
author_sort Hilmi Muhammad
collection DOAJ
description Introduction: Septic arthritis (SA) is considered an orthopedic emergency especially when occurring in infants yet the gold standard for its management is yet to be determined with only a scanty amount of research carried out the detailed outcomes information from different types of treatment used. This review identifies the detailed outcomes of infants with knee SA managed by various types of therapy. Material and methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards were used as guidelines in constructing this review. The study protocol was registered into the International Prospective Register of Systematic Reviews database prior to this review commencement (CRD42022379017). In October 2022, a thorough search was first conducted on PubMed, Cochrane Library, Scopus, and Web of Science. We focused on including findings with the population of interest being infants with knee SA who underwent various types of therapy consisting of surgical intervention and antibiotic administration with detailed outcomes. Results: A total of 14 articles were included, extracting detailed outcomes of infantile knee SA cases managed by different treatment choices. Only 3 articles reported the full information regarding the patient's outcomes where the patient's quality of life was the most reported information followed by range of motion and laboratory evaluation in 8 studies, and radiographic evaluation in 7 studies. Conclusion: Detailed patient outcomes and specific data regarding the patient's demographics including risk factors are needed to construct the guidelines for infantile knee SA for more uniform management consisting of surgical intervention and antibiotic administration with its duration.
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spelling doaj-art-4cfe573efab440d9a1e6e6b82d83d7992025-01-13T04:19:20ZengElsevierJournal of Orthopaedic Reports2773-157X2025-06-0142100518Management outcome of knee septic arthritis in neonates and infants:A systematic reviewHilmi Muhammad0Rahadyan Magetsari1Alfin Ihza Trimahendra2Paramita Ayu Saraswati3Pediatric Sub-Division, Orthopedics and Traumatology Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Corresponding author. Department of Surgery, Orthopedics and Traumatology Division, Sardjito General Hospital, Jl. Kesehatan No. 1, Yogyakarta, 55281, Indonesia.Orthopedics and Traumatology Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, IndonesiaFaculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, IndonesiaOrthopedics and Traumatology Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, IndonesiaIntroduction: Septic arthritis (SA) is considered an orthopedic emergency especially when occurring in infants yet the gold standard for its management is yet to be determined with only a scanty amount of research carried out the detailed outcomes information from different types of treatment used. This review identifies the detailed outcomes of infants with knee SA managed by various types of therapy. Material and methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards were used as guidelines in constructing this review. The study protocol was registered into the International Prospective Register of Systematic Reviews database prior to this review commencement (CRD42022379017). In October 2022, a thorough search was first conducted on PubMed, Cochrane Library, Scopus, and Web of Science. We focused on including findings with the population of interest being infants with knee SA who underwent various types of therapy consisting of surgical intervention and antibiotic administration with detailed outcomes. Results: A total of 14 articles were included, extracting detailed outcomes of infantile knee SA cases managed by different treatment choices. Only 3 articles reported the full information regarding the patient's outcomes where the patient's quality of life was the most reported information followed by range of motion and laboratory evaluation in 8 studies, and radiographic evaluation in 7 studies. Conclusion: Detailed patient outcomes and specific data regarding the patient's demographics including risk factors are needed to construct the guidelines for infantile knee SA for more uniform management consisting of surgical intervention and antibiotic administration with its duration.http://www.sciencedirect.com/science/article/pii/S2773157X24002133Septic arthritisSystematic reviewPediatricsOrthopedic
spellingShingle Hilmi Muhammad
Rahadyan Magetsari
Alfin Ihza Trimahendra
Paramita Ayu Saraswati
Management outcome of knee septic arthritis in neonates and infants:A systematic review
Journal of Orthopaedic Reports
Septic arthritis
Systematic review
Pediatrics
Orthopedic
title Management outcome of knee septic arthritis in neonates and infants:A systematic review
title_full Management outcome of knee septic arthritis in neonates and infants:A systematic review
title_fullStr Management outcome of knee septic arthritis in neonates and infants:A systematic review
title_full_unstemmed Management outcome of knee septic arthritis in neonates and infants:A systematic review
title_short Management outcome of knee septic arthritis in neonates and infants:A systematic review
title_sort management outcome of knee septic arthritis in neonates and infants a systematic review
topic Septic arthritis
Systematic review
Pediatrics
Orthopedic
url http://www.sciencedirect.com/science/article/pii/S2773157X24002133
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