Redox engineering of thermophilic fungus Myceliophthora thermophila enhances production of L‑malic acid by consolidated bioprocessing

Redox engineering of thermophilic fungus Myceliophthora thermophila enhances production of L‑malic acid by consolidated bioprocessing

Consolidated bioprocessing (CBP) is a promising strategy for low-cost malic acid production from plant biomass. In this study, we report a comprehensive redox engineering strategy to redirect reducing equivalents towards the reductive tricarboxylic acid (rTCA) pathway for enhanced malic acid product...

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Bibliographic Details
Main Authors: Yuying Zhang, Rui Fan, Taju Wu, Shuying Gu, Defei Liu, Liangcai Lin, Min Wang, Jingen Li, Chaoguang Tian
Format: Article
Language:English
Published: Taylor & Francis Group 2025-06-01
Series:Mycology
Subjects:
Myceliophthora
consolidated bioprocessing
cofactor engineering
rTCA pathway
malic acid
Online Access:https://www.tandfonline.com/doi/10.1080/21501203.2025.2509017
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https://www.tandfonline.com/doi/10.1080/21501203.2025.2509017

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