Identification of potential molecular targets of luteolin in the treatment of hepatocellular carcinoma based on network pharmacology and transcriptome sequencing technology

Identification of potential molecular targets of luteolin in the treatment of hepatocellular carcinoma based on network pharmacology and transcriptome sequencing technology

Abstract Objective This study aims to identify potential target genes of luteolin (LUT) for treating hepatocellular carcinoma (HCC) through integrated in vitro experiments, network pharmacology, bioinformatics, and transcriptome sequencing (RNA-seq). Methods Potential LUT-associated therapeutic targ...

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Bibliographic Details
Main Authors: Yunqi Han, Huijun Wu, Xin Zhang, Wei Lv, Yang Xiong, Xinyuan Tian, Yunfeng Xiao, Hongwei Cui
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Hepatocellular carcinoma
Luteolin
Transcriptomics
Network pharmacology
Signaling pathway
Online Access:https://doi.org/10.1007/s12672-025-03144-4
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https://doi.org/10.1007/s12672-025-03144-4

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