Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer

Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer

Macrophages are pivotal in driving breast tumor development, progression, and resistance to treatment, particularly in estrogen receptor-positive (ER+) tumors, where they infiltrate the tumor microenvironment (TME) influenced by cancer cell-secreted factors. By analyzing single-cell RNA sequencing d...

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Bibliographic Details
Main Authors: Sanghoon Lee, Youngbin Cho, Yiting Li, Ruxuan Li, Angela Wong Lau, Matthew S. Laird, Daniel Brown, Priscilla McAuliffe, Adrian V. Lee, Steffi Oesterreich, Ioannis K. Zervantonakis, Hatice Ulku Osmanbeyoglu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
Tumor associated macrophages
S100A11
tumor microenvironment
macrophage infiltration
monocyte infiltration
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2429186
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https://www.tandfonline.com/doi/10.1080/2162402X.2024.2429186

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