Bioengineered cardiovascular bypass grafts via in vivo self-assembly of scaffold-guided tubular tissue in rats

Bioengineered cardiovascular bypass grafts via in vivo self-assembly of scaffold-guided tubular tissue in rats

Abstract Cardiovascular bypass grafting remains a crucial therapeutic approach for complex atherosclerotic diseases. However, the clinical application of traditional grafts is hampered by limited autologous vessel availability, while the translational potential of fully cellular self-assembled vascu...

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Bibliographic Details
Main Authors: Shiqi Hu, Xiuhong Sun, Rui Zhou, Kai Fu, Yunfei Mo, Jialin Xu, Xiaoyan Shen, Shiwen Liu, Yuqing Niu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Nanobiotechnology
Subjects:
Scaffold-guided
Self-assembly
Bioengineered cardiovascular bypass graft
Tubular tissue morphogenesis
Vascular reconstruction
Online Access:https://doi.org/10.1186/s12951-025-03664-9
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https://doi.org/10.1186/s12951-025-03664-9

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