Characterization of cross-reactive, non-neutralizing monoclonal antibodies against a pandemic GII.4 norovirus variant

ABSTRACT Antibodies are thought to play a major role in protection against human norovirus infection. Mouse humoral responses closely mimic those of humans; thus, mouse models are used to characterize norovirus epitopes on the major viral capsid protein, VP1. We have developed a panel of mouse monoc...

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Bibliographic Details
Main Authors: Lauren A. Ford-Siltz, Kentaro Tohma, Kyle Kihn, Joseph A. Kendra, Daniel Deredge, Patrick Wintrode, Yamei Gao, Gabriel I. Parra
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.01143-24
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