A Target to Combat Antibiotic Resistance: Biochemical and Biophysical Characterization of 3-Dehydroquinate Dehydratase from Methicillin-Resistant <i>Staphylococcus aureus</i>

A Target to Combat Antibiotic Resistance: Biochemical and Biophysical Characterization of 3-Dehydroquinate Dehydratase from Methicillin-Resistant <i>Staphylococcus aureus</i>

Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is associated with the acquisition of nosocomial infections, community-acquired infections, and infections related to livestock animals. In the pursuit of molecular targets in the development process of antibacterial drugs, enzyme...

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Main Authors: Alfredo Téllez-Valencia, Jesús Oria-Hernández, Adriana Castillo-Villanueva, Erick Sierra-Campos, Mónica Valdez-Solana, Jorge Cisneros-Martínez, Claudia Avitia-Domínguez
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Microbiology Research
Subjects:
MRSA
3-dehydroquinate dehydratase
enzyme kinetics
biochemical characterization
thermodynamic parameters
antibiotic resistance
Online Access:https://www.mdpi.com/2036-7481/15/4/155
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