Pancreatic Safety of Tirzepatide and Its Effects on Islet Cell Function: A Systematic Review and Meta‐Analysis

Pancreatic Safety of Tirzepatide and Its Effects on Islet Cell Function: A Systematic Review and Meta‐Analysis

ABSTRACT Background Endogenous glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) regulate islet cell function. GLP‐1 receptor agonists (GLP‐1RAs) have been associated with an elevated risk of acute pancreatitis. Data on the pancreatic safety of tirzepatide (a dua...

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Bibliographic Details
Main Authors: A. B. M. Kamrul‐Hasan, Sunetra Mondal, Deep Dutta, Lakshmi Nagendra, Mohammed Ruhul Kabir, Joseph M. Pappachan
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Obesity Science & Practice
Subjects:
insulin resistance
islet cell function
lipase
pancreatic amylase
pancreatitis
tirzepatide
Online Access:https://doi.org/10.1002/osp4.70032
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https://doi.org/10.1002/osp4.70032

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