Maternal and lactogenic immunity in gestating sows induced by adenoviruses expressing mucosal immunogens derived from porcine epidemic diarrhea virus

Maternal and lactogenic immunity in gestating sows induced by adenoviruses expressing mucosal immunogens derived from porcine epidemic diarrhea virus

Abstract Porcine epidemic diarrhea virus (PEDV) is a significant pathogen that causes severe diarrhea and high mortality rates in piglets. Thus, maternal and lactogenic immunity is a key success in protecting piglets from PEDV. Here, we developed four recombinant adenovirus (rAd)-based vaccine candi...

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Main Authors: Namphueng Butkhot, Thotsapol Kaewchomphunuch, Pimploy Rattanaamnuaychai, Kanokporn Polyiam, Panida Chanapiwat, Natharin Ngamwongsatit, Yaowaluck Maprang Roshorm, Kampon Kaeoket
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Animal Diseases
Subjects:
Lactogenic immunity
Mucosal adjuvant
Neutralizing antibody
PEDV
Recombinant adenovirus vaccine
Online Access:https://doi.org/10.1186/s44149-025-00185-8
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