Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers

SUMMARY: Ganoderma Lucidum (G. lucidum) is an edible mushroom and it has been used as a medicinal fungus for centuries. We evaluated the efficacy of G. lucidum on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers. A total...

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Main Authors: Junyan Wang, Mahmoud Mostafa Azzam, Taidi Xiong, Yitong Wang, Jinling Ye, Qiuli Fan, Danlei Xu, Fayuan Ding, Zhonggang Cheng, Abdulaziz A. Alabdullatif, Rashed Alhotan, Shouqun Jiang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Applied Poultry Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1056617124000898
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author Junyan Wang
Mahmoud Mostafa Azzam
Taidi Xiong
Yitong Wang
Jinling Ye
Qiuli Fan
Danlei Xu
Fayuan Ding
Zhonggang Cheng
Abdulaziz A. Alabdullatif
Rashed Alhotan
Shouqun Jiang
author_facet Junyan Wang
Mahmoud Mostafa Azzam
Taidi Xiong
Yitong Wang
Jinling Ye
Qiuli Fan
Danlei Xu
Fayuan Ding
Zhonggang Cheng
Abdulaziz A. Alabdullatif
Rashed Alhotan
Shouqun Jiang
author_sort Junyan Wang
collection DOAJ
description SUMMARY: Ganoderma Lucidum (G. lucidum) is an edible mushroom and it has been used as a medicinal fungus for centuries. We evaluated the efficacy of G. lucidum on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers. A total of 216 one-day-old broiler chickens were randomly assigned to 3 treatment groups: a basal control diet with 0 mg/kg (G. lucidum), 300 mg/kg (G. lucidum), and 600 mg/kg (G. lucidum) for 50 d. The findings showed that G. lucidum showed an insignificant improvement in body weight and average body weight gain (P = 0.06 (during the early fattening period, and reduced the mortality rate (P < 0.001). In addition, dietary G. lucidum imposed changes in plasma indices, in a dose- and age-dependent manner. G. lucidum treatments increased plasma levels of superoxide dismutase activity (T-SOD) and interferon gamma (IFN-γ) at 21 d of age and decreased plasma activity of aspartate aminotransferase (AST) at 50 d of age. Compared to the control group, the levels of plasma urea nitrogen (UN) and inducible nitric oxide synthase (iNOS) decreased (P < 0.05) at a low dose of 300 mg G. lucidum/kg and interleukin 6 (IL-6) increased at a high dose of 600 mg G. lucidum/kg at 21 d of age. Plasma immunoglobulin A (IgA) levels increased (P < 0.05) at a high dose of 600 mg G. lucidum/kg, while malondialdehyde (MDA) decreased at a low dose of 300 mg G. lucidum/kg at 50 d of age. A significant increase (P < 0.05) in succinate dehydrogenase (SDH) activity in the liver was observed in birds fed 600 mg G. lucidum/kg. G. lucidum treatments increased (P = 0.003) mRNA expressions of jejunal B-cell lymphoma/leukemia-2 (Bcl-2). No differences were observed in the physicochemical indices of meat, except for redness (a*), which was lower (P = 0.02) in birds fed G. lucidum at a high dose of 600 mg/kg compared to the control diet. The findings suggest that G. lucidum would be considered as a feed supplement inclusion with possible ameliorative changes on broilers health status.
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spelling doaj-art-4aef99e6d08644008b06a6117465bac32024-12-05T05:19:38ZengElsevierJournal of Applied Poultry Research1056-61712024-12-01334100491Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilersJunyan Wang0Mahmoud Mostafa Azzam1Taidi Xiong2Yitong Wang3Jinling Ye4Qiuli Fan5Danlei Xu6Fayuan Ding7Zhonggang Cheng8Abdulaziz A. Alabdullatif9Rashed Alhotan10Shouqun Jiang11Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR China; Binhai Agricultural College, Guangdong Ocean University, Zhanjiang, Guangdong, 524088, PR ChinaDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh 11451, Saudi ArabiaInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR China; Department of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh 11451, Saudi ArabiaInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR China; Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, PR ChinaInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR ChinaInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR ChinaRensselaer Polytechnic Institute, Troy, NY 12180, USAInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR ChinaInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR ChinaDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh 11451, Saudi ArabiaInstitute of Animal Science, Guangdong Academy of Agricultural Sciences, Key Laboratory of Animal Nutrition and Feed Science (South China) of Ministry of Agriculture and Rural Affairs, State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangzhou, 510640, PR China; Corresponding author:SUMMARY: Ganoderma Lucidum (G. lucidum) is an edible mushroom and it has been used as a medicinal fungus for centuries. We evaluated the efficacy of G. lucidum on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers. A total of 216 one-day-old broiler chickens were randomly assigned to 3 treatment groups: a basal control diet with 0 mg/kg (G. lucidum), 300 mg/kg (G. lucidum), and 600 mg/kg (G. lucidum) for 50 d. The findings showed that G. lucidum showed an insignificant improvement in body weight and average body weight gain (P = 0.06 (during the early fattening period, and reduced the mortality rate (P < 0.001). In addition, dietary G. lucidum imposed changes in plasma indices, in a dose- and age-dependent manner. G. lucidum treatments increased plasma levels of superoxide dismutase activity (T-SOD) and interferon gamma (IFN-γ) at 21 d of age and decreased plasma activity of aspartate aminotransferase (AST) at 50 d of age. Compared to the control group, the levels of plasma urea nitrogen (UN) and inducible nitric oxide synthase (iNOS) decreased (P < 0.05) at a low dose of 300 mg G. lucidum/kg and interleukin 6 (IL-6) increased at a high dose of 600 mg G. lucidum/kg at 21 d of age. Plasma immunoglobulin A (IgA) levels increased (P < 0.05) at a high dose of 600 mg G. lucidum/kg, while malondialdehyde (MDA) decreased at a low dose of 300 mg G. lucidum/kg at 50 d of age. A significant increase (P < 0.05) in succinate dehydrogenase (SDH) activity in the liver was observed in birds fed 600 mg G. lucidum/kg. G. lucidum treatments increased (P = 0.003) mRNA expressions of jejunal B-cell lymphoma/leukemia-2 (Bcl-2). No differences were observed in the physicochemical indices of meat, except for redness (a*), which was lower (P = 0.02) in birds fed G. lucidum at a high dose of 600 mg/kg compared to the control diet. The findings suggest that G. lucidum would be considered as a feed supplement inclusion with possible ameliorative changes on broilers health status.http://www.sciencedirect.com/science/article/pii/S1056617124000898broilerGanoderma lucidumhealthmeat quality
spellingShingle Junyan Wang
Mahmoud Mostafa Azzam
Taidi Xiong
Yitong Wang
Jinling Ye
Qiuli Fan
Danlei Xu
Fayuan Ding
Zhonggang Cheng
Abdulaziz A. Alabdullatif
Rashed Alhotan
Shouqun Jiang
Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers
Journal of Applied Poultry Research
broiler
Ganoderma lucidum
health
meat quality
title Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers
title_full Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers
title_fullStr Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers
title_full_unstemmed Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers
title_short Effects of Ganoderma Lucidum supplementation on the growth performance, biochemical blood parameters, antioxidant and immunity status, and meat quality in slow-growing broilers
title_sort effects of ganoderma lucidum supplementation on the growth performance biochemical blood parameters antioxidant and immunity status and meat quality in slow growing broilers
topic broiler
Ganoderma lucidum
health
meat quality
url http://www.sciencedirect.com/science/article/pii/S1056617124000898
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