Integrity of RNA in long-term-stored cervical liquid-based cytology samples: implications for biomarker research

Integrity of RNA in long-term-stored cervical liquid-based cytology samples: implications for biomarker research

Biobanks of cervical screening (LBC) samples annotated with disease status are an invaluable resource to support the development of tools for the risk stratification of disease. Although there is growing interest in the assessment of RNA-based biomarkers, little is known on the suitability and durab...

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Bibliographic Details
Main Authors: Madeleine P J White, Andrew Stevenson, Hana Elasifer, Chris Davis, Kyriaki Nomikou, Kate Cuschieri, Sheila V Graham
Format: Article
Language:English
Published: Taylor & Francis Group 2024-06-01
Series:BioTechniques
Subjects:
biobanking
cervical screening
reverse transcriptase quantitative PCR
RNA biomarkers
RNA quality
storage temperature
Online Access:https://www.tandfonline.com/doi/10.2144/btn-2023-0112
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https://www.tandfonline.com/doi/10.2144/btn-2023-0112

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