Nutritional state-dependent modulation of insulin-producing cells in Drosophila

Nutritional state-dependent modulation of insulin-producing cells in Drosophila

Insulin plays a key role in metabolic homeostasis. Drosophila insulin-producing cells (IPCs) are functional analogues of mammalian pancreatic beta cells and release insulin directly into circulation. To investigate the in vivo dynamics of IPC activity, we quantified the effects of nutritional and in...

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Bibliographic Details
Main Authors: Rituja S Bisen, Fathima Mukthar Iqbal, Federico Cascino-Milani, Till Bockemühl, Jan M Ache
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
Insulin
incretin effect
metabolic homeostasis
in vivo electrophysiology
neuronal circuits
locomotion
Online Access:https://elifesciences.org/articles/98514
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