Structural analysis of the stable form of fibroblast growth factor 2 – FGF2-STAB

Structural analysis of the stable form of fibroblast growth factor 2 – FGF2-STAB

Fibroblast growth factor 2 (FGF2) is a signaling protein that plays a significant role in tissue development and repair. FGF2 binds to fibroblast growth factor receptors (FGFRs) alongside its co-factor heparin, which protects FGF2 from degradation. The binding between FGF2 and FGFRs induces intracel...

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Bibliographic Details
Main Authors: Gabin de La Bourdonnaye, Martin Marek, Tereza Ghazalova, Jiri Damborsky, Petr Pachl, Jiri Brynda, Veronika Stepankova, Radka Chaloupkova
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Structural Biology: X
Subjects:
Stabilized fibroblast growth factor 2
X-ray structural analysis
Protein flexibility
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152424000175
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