Searching for the ‘X’ factor: investigating the genetics of primary ovarian insufficiency

Searching for the ‘X’ factor: investigating the genetics of primary ovarian insufficiency

Abstract Primary ovarian insufficiency (POI) is the cessation of ovarian function before the age of 40. The causes of POI are heterogeneous, but substantial evidence exists to support a genetic basis of POI, particularly in the critical involvement of genes on the X chromosome. Recent studies have r...

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Bibliographic Details
Main Authors: Anya Knight, Sara Sugin, Andrea Jurisicova
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Ovarian Research
Subjects:
Primary ovarian insufficiency
X chromosome inactivation
Gene dosage
Folliculogenesis
Oogenesis
Ovarian phenotype
Online Access:https://doi.org/10.1186/s13048-024-01555-5
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https://doi.org/10.1186/s13048-024-01555-5

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