Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis

Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis

The induction of adipose thermogenesis plays a critical role in maintaining body temperature and improving metabolic homeostasis to combat obesity. β3-adrenoceptor (β3-AR) is widely recognized as a canonical β-adrenergic G-protein-coupled receptor (GPCR) that plays a crucial role in mediating adipos...

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Bibliographic Details
Main Authors: Zewei Zhao, Longyun Hu, Bigui Song, Tao Jiang, Qian Wu, Jiejing Lin, Xiaoxiao Li, Yi Cai, Jin Li, Bingxiu Qian, Siqi Liu, Jilu Lang, Zhonghan Yang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
adipose
ADGRA3
thermogenesis
obesity
GPCR
hesperetin
Online Access:https://elifesciences.org/articles/100205
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https://elifesciences.org/articles/100205

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