Safe and Efficient Preparative Approach to Chiral α-Chloroketones Based on In-Flow Generated Diazomethane
α-Chloroketones are valuable semi-products in the organic synthesis and pharmaceutical industry. In particular, they are used as key building blocks for the production of HIV protease inhibitors, such as atazanavir and darunavir. A well-known approach to their synthesis involves the Arndt-Eistert ho...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy (Kharkiv)
2024-12-01
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| Series: | Журнал органічної та фармацевтичної хімії |
| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/324406 |
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