A model-based design strategy to engineer miRNA-regulated detection systems

miRNAs are promising diagnostic biomarkers. These small RNA molecules are always present in the human body but become dysregulated when a person develops certain diseases. Although the detection of these biomarkers in cell-free tests is ongoing work, current systems often focus solely on detecting t...

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Bibliographic Details
Main Authors: Renske J. Verkuijlen, Robert W. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Systems Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fsysb.2025.1601854/full
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