Ferulic Acid Interferes with Radioactive Intestinal Injury Through the DJ-1-Nrf2 and Sirt1-NF-κB-NLRP3 Pathways

Ferulic Acid Interferes with Radioactive Intestinal Injury Through the DJ-1-Nrf2 and Sirt1-NF-κB-NLRP3 Pathways

Radiation-induced intestinal injury is a common complication of radiotherapy for abdominal and pelvic malignancies. Due to its rapid proliferation, the small intestine is particularly sensitive to radiation, making it a critical factor limiting treatment. Ferulic acid (FA), a derivative of cinnamic...

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Bibliographic Details
Main Authors: Xuemei Zhang, Haoyu Zhang, Mingyue Huang, Yu Mei, Changkun Hu, Congshu Huang, Huiting Zhang, Xue Wei, Yue Gao, Zengchun Ma
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Molecules
Subjects:
radiation injury
intestine
ferulic acid
oxidative damage
inflammatory injury
Online Access:https://www.mdpi.com/1420-3049/29/21/5072
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