MRI表观弥散系数预测肝细胞癌肿瘤免疫细胞浸润
目的探索MRI弥散加权成像(DWI)的表观弥散系数(ADC)评估肝细胞癌(HCC)免疫细胞浸润的可行性。方法纳入初治HCC患者24例,所有患者均于术前行MRI DWI检查。收集患者术后1 h内新鲜组织块,分别取瘤内、瘤旁2 cm内组织块。采用多色流式细胞分析术获得组织内炎性细胞、T细胞、B细胞、CD4<sup>+</sup> T细胞、CD8<sup>+</sup> T细胞以及CD8<sup>+</sup>PD1<sup>+</sup> T细胞、调节性T细胞、巨噬细胞比率。在MRI ADC图上测量肿瘤...
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Main Authors: | , , , , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
2021-03-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
Subjects: | |
Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/7775652/ |
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