Apolipoprotein L1 risk alleles: extravasation of T. brucei and insights into lupus nephritis pathogenicity—a scoping review
Abstract Background and objectives Genetic investigations have associated APOL1 risk alleles (G1/G2) with lupus nephritis (LN) and, paradoxically, protection against Trypanosoma brucei infection. This review aims to elucidate their shared pathogenic mechanisms by investigating T. brucei infection pr...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
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| Series: | Journal of Rare Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44162-025-00093-y |
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