Design, Synthesis, Anticancer Screening and Virtual Analysis of New 7-Sulfonyldiazepan- and 7-Sulfonylpiperazine-substituted Oxazolo[4,5-d]pyrimidines

The design of novel anticancer agents has been advanced by applying machine learning techniques, leading to several classification and regression structure-activity relationship models specifically tailored for the human glioblastoma SNB-75. Using these models, a virtual library was screened to iden...

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Bibliographic Details
Main Authors: Stepan G Pilyo, Maryna V Kachaeva, Victor V Zhirnov, Vasyl V Kovalishyn, Ivan V Semenyuta, Yevheniia S Velihina, Larysa O Metelytsia, Vladimir Brovarets
Format: Article
Language:English
Published: Georg Thieme Verlag KG
Series:SynOpen
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-2688-5534
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