Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors

Background and Objective. When radiologists diagnose lung diseases in chest radiography, they can miss some lung nodules overlapped with ribs or clavicles. Dual-energy subtraction (DES) imaging performs well because it can produce soft tissue images, in which the bone components in chest radiography...

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Main Authors: Yunbi Liu, Wei Yang, Guangnan She, Liming Zhong, Zhaoqiang Yun, Yang Chen, Ni Zhang, Liwei Hao, Zhentai Lu, Qianjin Feng, Wufan Chen
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Applied Bionics and Biomechanics
Online Access:http://dx.doi.org/10.1155/2019/9806464
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author Yunbi Liu
Wei Yang
Guangnan She
Liming Zhong
Zhaoqiang Yun
Yang Chen
Ni Zhang
Liwei Hao
Zhentai Lu
Qianjin Feng
Wufan Chen
author_facet Yunbi Liu
Wei Yang
Guangnan She
Liming Zhong
Zhaoqiang Yun
Yang Chen
Ni Zhang
Liwei Hao
Zhentai Lu
Qianjin Feng
Wufan Chen
author_sort Yunbi Liu
collection DOAJ
description Background and Objective. When radiologists diagnose lung diseases in chest radiography, they can miss some lung nodules overlapped with ribs or clavicles. Dual-energy subtraction (DES) imaging performs well because it can produce soft tissue images, in which the bone components in chest radiography were almost suppressed but the visibility of nodules and lung vessels was still maintained. However, most routinely available X-ray machines do not possess the DES function. Thus, we presented a data-driven decomposition model to perform virtual DES function for decomposing a single conventional chest radiograph into soft tissue and bone images. Methods. For a given chest radiograph, similar chest radiographs with corresponding DES soft tissue and bone images are selected from the training database as exemplars for decomposition. The corresponding fields between the observed chest radiograph and the exemplars are solved by a hierarchically dense matching algorithm. Then, nonparametric priors of soft tissue and bone components are constructed by sampling image patches from the selected soft tissue and bone images according to the corresponding fields. Finally, these nonparametric priors are integrated into our decomposition model, the energy function of which is efficiently optimized by an iteratively reweighted least-squares scheme (IRLS). Results. The decomposition method is evaluated on a data set of posterior-anterior DES radiography (503 cases), as well as on the JSRT data set. The proposed method can produce soft tissue and bone images similar to those produced by the actual DES system. Conclusions. The proposed method can markedly reduce the visibility of bony structures in chest radiographs and shows potential to enhance diagnosis.
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spelling doaj-art-487eff434d37436e98ed5c26eac5d2822025-02-03T05:52:55ZengWileyApplied Bionics and Biomechanics1176-23221754-21032019-01-01201910.1155/2019/98064649806464Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image PriorsYunbi Liu0Wei Yang1Guangnan She2Liming Zhong3Zhaoqiang Yun4Yang Chen5Ni Zhang6Liwei Hao7Zhentai Lu8Qianjin Feng9Wufan Chen10School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaLaboratory of Image Science and Technology, Southeast University, Nanjing 211189, ChinaNanfang Hospital, Southern Medical University, Guangzhou 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, ChinaBackground and Objective. When radiologists diagnose lung diseases in chest radiography, they can miss some lung nodules overlapped with ribs or clavicles. Dual-energy subtraction (DES) imaging performs well because it can produce soft tissue images, in which the bone components in chest radiography were almost suppressed but the visibility of nodules and lung vessels was still maintained. However, most routinely available X-ray machines do not possess the DES function. Thus, we presented a data-driven decomposition model to perform virtual DES function for decomposing a single conventional chest radiograph into soft tissue and bone images. Methods. For a given chest radiograph, similar chest radiographs with corresponding DES soft tissue and bone images are selected from the training database as exemplars for decomposition. The corresponding fields between the observed chest radiograph and the exemplars are solved by a hierarchically dense matching algorithm. Then, nonparametric priors of soft tissue and bone components are constructed by sampling image patches from the selected soft tissue and bone images according to the corresponding fields. Finally, these nonparametric priors are integrated into our decomposition model, the energy function of which is efficiently optimized by an iteratively reweighted least-squares scheme (IRLS). Results. The decomposition method is evaluated on a data set of posterior-anterior DES radiography (503 cases), as well as on the JSRT data set. The proposed method can produce soft tissue and bone images similar to those produced by the actual DES system. Conclusions. The proposed method can markedly reduce the visibility of bony structures in chest radiographs and shows potential to enhance diagnosis.http://dx.doi.org/10.1155/2019/9806464
spellingShingle Yunbi Liu
Wei Yang
Guangnan She
Liming Zhong
Zhaoqiang Yun
Yang Chen
Ni Zhang
Liwei Hao
Zhentai Lu
Qianjin Feng
Wufan Chen
Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors
Applied Bionics and Biomechanics
title Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors
title_full Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors
title_fullStr Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors
title_full_unstemmed Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors
title_short Soft Tissue/Bone Decomposition of Conventional Chest Radiographs Using Nonparametric Image Priors
title_sort soft tissue bone decomposition of conventional chest radiographs using nonparametric image priors
url http://dx.doi.org/10.1155/2019/9806464
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