(+)-JQ-1 alleviates cardiac injury in myocardial infarction by inhibiting ferroptosis through the NAMPT/SIRT1 pathway

Abstract Myocardial infarction (MI) remains one of the leading causes of mortality worldwide, and cardiomyocyte death plays a critical role in cardiac remodeling after MI. Ferroptosis is a recently identified form of iron-dependent programmed cell death that has been shown to be involved in the prog...

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Bibliographic Details
Main Authors: Mengxue Yang, Ting Wang, Jingrong Shao, Xinna Ran, Rui Xiao, Rui Zhao, Chunyan Wu, Ming Ji, Weiping Tian, Huabing Sun, Jiao Liu, Shengkai Zuo
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07880-x
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