Protein Quakes in Redox Metalloenzymes: Clues to Molecular Enzyme Conductivity Triggered by Binding of Small Substrate Molecules

Protein Quakes in Redox Metalloenzymes: Clues to Molecular Enzyme Conductivity Triggered by Binding of Small Substrate Molecules

Abstract Multicentre redox metalloproteins undergo conformational changes on electrochemical surfaces, or on enzyme substrate binding. The two‐centre copper enzymes, laccase (Type I and TypeII/III Cu) and nitrite reductase (CuNIR) (Type I and Type II Cu) are examples. With some exceptions, these enz...

Full description

Saved in:
Bibliographic Details
Main Authors: Henrik Bohr, Irene Shim, Jens Ulstrup, Xinxin Xiao
Format: Article
Language:English
Published: Wiley-VCH 2024-12-01
Series:ChemistryOpen
Subjects:
Two-centre copper nitrite reductase
intramolecular electron transfer
ab initio electronic stucture calculations
electrochemical STM/AFM
Frontier orbitals
Online Access:https://doi.org/10.1002/open.202400190
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/open.202400190

Similar Items