Targeting the molecular crosstalk between diabetes and lung cancer for therapeutic intervention

Targeting the molecular crosstalk between diabetes and lung cancer for therapeutic intervention

Abstract Purpose This review investigates the complex association between type 2 diabetes mellitus (T2DM) and lung cancer, focusing on shared risk factors, molecular mechanisms, and clinical implications. We aim to quantify the impact of T2DM on lung cancer incidence, progression, and treatment resp...

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Main Authors: Alireza Azani, Nahal Aghajamal Avval, Mohammad Saeed Soleimani Meigoli, Mahshid Imankhan, Pouya Asgari, Gholamreza Ebrahimisaraj, Reza Morovatshoar, Ahmad Mir Hosseini, Seyedeh Tarlan Mirzohreh, Masoumeh Nouri, Hossein Azari Bostanabad, Qumars Behfar, Fahimeh Bayrami, Malihe Sharafi
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Lung cancer
Diabetes
Type 2 diabetes mellitus
Small cell lung cancer
Non-small cell lung cancer
Insulin-like growth factor
Online Access:https://doi.org/10.1007/s12672-025-03264-x
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https://doi.org/10.1007/s12672-025-03264-x

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