Post hoc analysis of a randomized placebo-controlled trial suggests potential visual benefits of branched-chain amino acids in retinitis pigmentosa

Post hoc analysis of a randomized placebo-controlled trial suggests potential visual benefits of branched-chain amino acids in retinitis pigmentosa

Abstract This study assessed and compensated for baseline differences in a randomized clinical trial of branched-chain amino acids (BCAAs) in patients with retinitis pigmentosa (RP). Seventy patients with eyes showing a mean deviation (MD) of − 5.0 to − 25.0 dB in the Humphrey visual-field (HFA 10-2...

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Main Authors: Tomoko Hasegawa, Hanako Ohashi Ikeda, Hiroyasu Abe, Yoko Amino, Takayuki Nakagawa, Harue Tada, Manabu Miyata, Akio Oishi, Satoshi Morita, Akitaka Tsujikawa
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Branched-chain amino acid
Humphrey visual-field test
Placebo effect
Retinitis pigmentosa
Online Access:https://doi.org/10.1038/s41598-025-07341-7
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https://doi.org/10.1038/s41598-025-07341-7

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