Clinical significance of serum estradiol monitoring in women receiving adjuvant aromatase inhibitor for hormone receptor-positive early breast cancer

Clinical significance of serum estradiol monitoring in women receiving adjuvant aromatase inhibitor for hormone receptor-positive early breast cancer

Purpose: The limited understanding of long-term estradiol (E2) suppression poses challenges to the effectiveness of adjuvant therapy with aromatase inhibitors (AI), necessitating comprehensive serum E2 monitoring to address this issue. Therefore, our objective was to investigate serum E2 levels in w...

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Main Authors: Shuqin Dai, Xingping Wu, Xuefang Huang, Jibin Li, Xi Wang, Shusen Wang, Jun Tang, Yanxia Shi, Xiaoming Xie, Fei Xu, Peng Liu, Jiajia Huang, Xinhua Xie, Xin An, Meiting Chen, Rouxi Hong, Wen Xia, Qiufan Zheng, Kuikui Jiang, Yongyi Zhong, Zhongyu Yuan, Yuanyuan Huang, Xiwen Bi, Cong Xue
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Breast
Subjects:
Aromatase inhibitor
Estradiol monitoring
Gonadotropin-releasing hormone agonists
Hormone receptor-positive early breast cancer
Liquid chromatography–tandem mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977624001498
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