Interpreting roles of mutations associated with the emergence of S. aureus USA300 strains using transcriptional regulatory network reconstruction

Interpreting roles of mutations associated with the emergence of S. aureus USA300 strains using transcriptional regulatory network reconstruction

The Staphylococcus aureus clonal complex 8 (CC8) is made up of several subtypes with varying levels of clinical burden; from community-associated methicillin-resistant S. aureus USA300 strains to hospital-associated (HA-MRSA) USA500 strains and ancestral methicillin-susceptible (MSSA) strains. This...

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Bibliographic Details
Main Authors: Saugat Poudel, Jason Hyun, Ying Hefner, Jon Monk, Victor Nizet, Bernhard O Palsson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
transcriptional regulatory network
GWAS
independent component analysis
Staphylococcus aureus
Online Access:https://elifesciences.org/articles/90668
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https://elifesciences.org/articles/90668

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