Cellular immunotherapy targeting CLL-1 for juvenile myelomonocytic leukemia

Cellular immunotherapy targeting CLL-1 for juvenile myelomonocytic leukemia

Abstract Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative disorder that predominantly affects infants and young children. Hematopoietic stem cell transplantation (HSCT) is standard of care, but post-HSCT relapse is common, highlighting the need for innovative therapies. While adoptive...

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Main Authors: Juwita Werner, Alex G. Lee, Chujing Zhang, Sydney Abelson, Sherin Xirenayi, Jose Rivera, Khadija Yousuf, Hanna Shin, Bonell Patiño-Escobar, Stefanie Bachl, Kamal Mandal, Abhilash Barpanda, Emilio Ramos, Adila Izgutdina, Sibapriya Chaudhuri, William C. Temple, Shubhmita Bhatnagar, Jackson K. Dardis, Julia Meyer, Carolina Morales, Soheil Meshinchi, Mignon L. Loh, Benjamin Braun, Sarah K. Tasian, Arun P. Wiita, Elliot Stieglitz
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59040-6
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https://doi.org/10.1038/s41467-025-59040-6

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