Glucose-induced STUB1-GOT2 axis promotes aspartate synthesis and mitochondrial dysfunction in bladder cancer
Abstract Aberrant glucose metabolism, a characteristic of malignant tumors, contributes to the development and progression of bladder cancer (BCa). However, the underlying mechanism by which aberrant glucose metabolism promotes BCa progression is still incompletely understood. Here, we demonstrate t...
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| Main Authors: | Yunqiang Xiong, Qianxi Dong, Hongji Hu, Zhongqi Li, Xiangpeng Zhan, Fuchun Zheng, Hao Wan, Jiahao Liu, Shuyu Wu, Wang Pan, Ruize Yuan, Jing Xiong, Ju Guo, Songhui Xu, Bin Fu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07840-5 |
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