Spatiotemporal characterization of extracellular matrix maturation in human artificial stromal-epithelial tissue substitutes

Spatiotemporal characterization of extracellular matrix maturation in human artificial stromal-epithelial tissue substitutes

Abstract Background Tissue engineering techniques offer new strategies to understand complex processes in a controlled and reproducible system. In this study, we generated bilayered human tissue substitutes consisting of a cellular connective tissue with a suprajacent epithelium (full-thickness stro...

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Main Authors:	Paula Ávila-Fernández, Miguel Etayo-Escanilla, David Sánchez-Porras, Ricardo Fernández-Valadés, Fernando Campos, Ingrid Garzón, Víctor Carriel, Miguel Alaminos, Óscar Darío García-García, Jesús Chato-Astrain
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Series:	BMC Biology
Subjects:	Extracellular matrix Artificial tissue substitutes Tissue engineering Epithelial-mesenchymal interaction Matrix maturation Basement membrane
Online Access:	https://doi.org/10.1186/s12915-024-02065-y
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