Spatiotemporal characterization of extracellular matrix maturation in human artificial stromal-epithelial tissue substitutes

Spatiotemporal characterization of extracellular matrix maturation in human artificial stromal-epithelial tissue substitutes

Abstract Background Tissue engineering techniques offer new strategies to understand complex processes in a controlled and reproducible system. In this study, we generated bilayered human tissue substitutes consisting of a cellular connective tissue with a suprajacent epithelium (full-thickness stro...

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Main Authors: Paula Ávila-Fernández, Miguel Etayo-Escanilla, David Sánchez-Porras, Ricardo Fernández-Valadés, Fernando Campos, Ingrid Garzón, Víctor Carriel, Miguel Alaminos, Óscar Darío García-García, Jesús Chato-Astrain
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Biology
Subjects:
Extracellular matrix
Artificial tissue substitutes
Tissue engineering
Epithelial-mesenchymal interaction
Matrix maturation
Basement membrane
Online Access:https://doi.org/10.1186/s12915-024-02065-y
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https://doi.org/10.1186/s12915-024-02065-y

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