Immune checkpoint therapy modeling of PD-1/PD-L1 blockades reveals subtle difference in their response dynamics and potential synergy in combination

Immune checkpoint therapy modeling of PD-1/PD-L1 blockades reveals subtle difference in their response dynamics and potential synergy in combination

Immune checkpoint therapy is one of the most promising immunotherapeutic methods that are likely able to give rise to durable treatment response for various cancer types. Despite much progress in the past decade, there are still critical open questions with particular regards to quantifying and pred...

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Bibliographic Details
Main Authors: Kamran Kaveh, Feng Fu
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:ImmunoInformatics
Subjects:
Cancer-immune interactions
Checkpoint inhibitors
Personalized immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119021000045
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http://www.sciencedirect.com/science/article/pii/S2667119021000045

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