Identification EXOSC4 as a novel autoantigen of interstitial lung disease in rheumatoid arthritis

Identification EXOSC4 as a novel autoantigen of interstitial lung disease in rheumatoid arthritis

Abstract Background Interstitial lung disease (ILD) is a common and severe comorbidity of rheumatoid arthritis (RA), yet reliable diagnostic biomarkers remain lacking. Alveolar type II (ATII) cells are widely recognized to play a key role in the pathogenesis of ILD. This study first aimed to screen...

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Main Authors: Chuanhui Yao, Xun Gong, Biyue Shang, Dan Dou, Weixiang Liu, Hui Xu, Yuchen Yang, Xieli Ma, Qiuwei Peng, Juan Jiao, Xiaopo Tang, Congmin Xia, Peng Chen, Quan Jiang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Rheumatoid arthritis
Interstitial lung disease
Alveolar type II cell
Autoantigen
Online Access:https://doi.org/10.1186/s12967-025-06667-0
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