Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications

Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications

Abstract Lack of standardization in biofoundries limits the scalability and efficiency of synthetic biology research. Here, we propose an abstraction hierarchy that organizes biofoundry activities into four interoperable levels: Project, Service/Capability, Workflow, and Unit Operation, effectively...

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Main Authors: Haseong Kim, Nathan J. Hillson, Byung-Kwan Cho, Bong Hyun Sung, Dae-Hee Lee, Dong-Myung Kim, Min-Kyu Oh, Matthew Wook Chang, Yong-Su Jin, Susan J. Rosser, Peter Vegh, Rennos Fragkoudis, Rosalind Le Feuvre, Nigel S. Scrutton, Marko Storch, Wonjae Seong, Paul S. Freemont, Seung-Goo Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61263-6
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https://doi.org/10.1038/s41467-025-61263-6

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