Exploring marine-derived bacterial compounds targeting the μ-opioid receptor agonists through metabolic profiling to molecular modeling

Abstract Given the severe side effects of prolonged morphine use, the search for safer alternatives is a global priority. This study investigates marine bacteria from sediments along the Bejaia coast, Algeria, to identify opioid-like bioactive compounds with potential analgesic properties. A total o...

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Bibliographic Details
Main Authors: Daouia Boudrahem, Omar Messaoudi, Sarah Balit, Mouloud Kecha, Joachim Wink, Chirag N. Patel
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-96411-x
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