Focal boosted IMRT treatment of prostate cancer to 84 Gy in 28 fractions: preliminary clinical outcomes, toxicity, and dosimetry

Focal boosted IMRT treatment of prostate cancer to 84 Gy in 28 fractions: preliminary clinical outcomes, toxicity, and dosimetry

IntroductionThe FLAME trial reported that focal boosting of prostate tumors up to 95 Gy in 35 fractions improves biochemical control (disease-free survival). However, this treatment (regimen) is not commonly used in the United States. We investigated a focally boosted treatment of 84 Gy in 28 fracti...

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Main Authors: Jacob Michael Hands, Michael J. Whalen, Shawn Haji-Momenian, Harold Frazier, Ramez Andrawis, Destie Provenzano, Julie E. Bauman, Fayez Estephan, Hamid Aghdam, Dongjun Chen, Sharad Goyal, Martin Ojong-Ntui, Yuan James Rao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
radiation oncologist
IMRT
SBRT
radiotoxicity
dosimetry
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1577359/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1577359/full

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