Conserved multiepitopes in Plasmodium falciparum STEVORs enable rational design of a fusion antigen vaccine construct with broad immunogenicity
There is no vaccine for severe malaria. STEVOR antigens on the surface of Plasmodium falciparum-infected red blood cells are implicated in severe malaria and are targeted by neutralizing antibodies, but their epitopes remain unknown. Using computational immunology, we identified highly immunogenic o...
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Main Authors: | Zhi-Shan Sun, Jing-Xian Yin, Han-Qing Zhao, Yin-shan Zhu, Shen-Bo Chen, Hai-Mo Shen, Bin Xu, Xiao-Nong Zhou, Tian-Yu Wang, Wan-Xuan Yang, Yi-Wen Duan, Jun-Hu Chen, Kokouvi Kassegne |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-08-01
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Series: | Emerging Microbes and Infections |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2025.2552783 |
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